I'm interested in hearing opinions about how questions that could potentially be answered in multiple stack exchange forums should be answered. The following question was asked on the main biology forum: Are alpha-ketoglutarate and glutamate involved in all transamination reactions?
A comment followed indicating that General Chemistry question were off-topic, with which I initially disagreed. Transamination reactions are critical to anapleurosis/catapleurosis of metabolic cycles, and I thought this clearly belonged in the biology forum with a
That user, a respected individual in this community, indicated that the question "lacks any biological background" and thus "Chemistry.SE would be better". I agreed with his comment, however, the OP subsequently indicated that similar question in the Chemisty.SE would be unanswerable by the chemistry community.
Are there strong feelings about that community that should be answering these questions, or how have similar situations be handled in the past?